Sentence examples for regulating target from inspiring English sources

Overall, this study provides novel evidence that non-hypoxic HIF-1α inherentlytly expressed in AI-resistant cells, upregulated by HER2-PI3K/Akt-mTOR pathway and is an important factor in letrozole-resistant breast cancer cells, regulating target genes such as BCRP and regulating AI responsiveness and cancer stem cell characteristic expression.

Taken together, we hypothesize that different combinatorial dimers formed by OsWRKY IIa proteins may exhibit different functions in regulating target gene expression.

Most importantly, polyamides are cell permeable and localize in the nucleus in various cultured cell lines and are capable of down regulating target genes in these cells.

This O-GlcNAc modified HDAC1 further functions in regulating the global histone acetylation level, and therefore influences the cell proliferation, invasion, and migration by regulating target genes in HepG2 cells (Zhu et al., 2016), suggesting the potential coordinative role in hepatic carcinoma.

Upon activation by PPARα ligands, PPARα heterodimerizes with retinoic acid receptor (RXR) regulating target gene expressions.

The exact molecular mechanisms of how p53 distinguishes between pro-apoptotic and cell cycle regulating target genes still remain unclear.

Riboregulators for regulating targeted gene expression have also been designed and produced in vitro as well as in vivo.

It is well documented that activated FoxO3 could move into nucleus to regulate target gene expression.

However, why cells use such sophisticated and intricate mechanisms to regulate target gene expression is a fascinating question.

Targeting the ETS1 interface might have great therapeutic value because ETS1 dimerizes itself or with other transcription factors to regulate target genes.

To assess whether FoxO3 and Smad2/3 could be activated simultaneously and cooperate to regulate target gene transcription, double immunostaining assays were performed.