For example, it has been shown that VPEs regulate systematic cell death induced by viral, aluminium and heat stress, which is mediated by caspase-1-like activity during PCD (Hatsugai et al. 2004b; Li et al. 2012; Kariya et al. 2013).
To better define the genetic pathways regulating sporulation, a systematic screen of the set of ~3300 nonessential Schizosaccharomyces pombe gene deletion mutants was performed to identify genes required for spore formation.
To study the transcriptional network in a systematic manner, regulating multiple endogenous genes is required, prompting the development of efficient technology for simultaneous regulation of multiple endogenous genes.
Since current gene therapy techniques are limited in that transfected genes are typically either in an "on" or "off" state [ 21], the expression of a transfected gene needs to be regulated in a systematic fashion for the effective treatment of many diseases.
Starr stated that "A profession is an occupation [that] regulates itself through systematic, required training and collegial discipline; that has a base in technical specialized knowledge; and has a service rather than a profit orientation, and is enshrined in its code of ethics" [ 28].
While the legislation provided additional resources for law enforcement and a systematic means for regulating the use of most psychoactive drugs, it also did away with mandatory minimum sentences and provided more support for treatment and research.
Although most of laws and legislation were meant to assert the British control on water resources and aquifers in Palestine and were also a means of gathering taxes from water usage, the British employed scientific and systematic methods for regulating the relation between the executive power and the water services' beneficiaries.
The laissez-faire attitude previously adopted for the sector has transformed into a systematic approach towards regulating teacher and leadership requirements, promoting and sustaining center-level quality standards, and directing the development and delivery of a good quality and appropriate curriculum and program.
Peter Lurie, deputy director of Public Citizens Health Research Groupp, said the delays in regulating the compound reflected what he called the administration's systematic underenforcement in occupational safety.
The present study provides a systematic view and working model of a transcriptional network regulating the formation and metabolism of the pulmonary surfactant system.
