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The observation that exposure to adenosine blocked the synergistic effect of combined DHFR and GSK3 inhibition opens the possibility that signaling events outside of those perturbed by changes in methylation may play a role in regulating pathway cross-talk.
These more standard approaches assume that the presence of a pathway component implies its activity, yet they do not capture the impact of phosphorylation state or cellular compartmentalization that are common mechanisms for regulating pathway activity.
Step 6: miRNA Regulating Pathway Cross-Talk.
Given that both SD and low temperature repress SFL, analogous flowering regulating pathway has not yet been characterized at molecular level.
Our goal was to develop an approach to quantify the cross-talk between pathways and to identify key miRNAs regulating pathway cross-talk.
In this work our goal was to develop an approach that could be able to quantify the cross-talk between pathways and to identify key miRNAs regulating pathway cross-talk.
Similar(51)
Two lines of evidence suggest hypotonic solutions might activate mechanotransduction machinery rather than ubiquitous volume regulating pathways.
Collectively, the present studies demonstrate mRNA:miRNA transcriptional responses following activated FGF signaling in lens cell culture system and predicted novel GRNs connected by multiple miRNAs regulating pathway-specific lens regulatory factors.
Epoxyeicosatrienoic acids (EETs) are cytochrome P450 epoxygenase metabolites of arachidonic acid involved in regulating pathways promoting cellular protection.
A homolog of type-B Arabidopsis response regulator (B-ARR, Bradi1g69480.1) was found in the cytokinin regulated pathway.
PCD is a tightly regulated pathway that accompanies the activation of specific biochemical pathways (Greenberg 1996).
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