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DSG inhibited 3T3-L1 adifferentiationentiandon and reduced adipocyte size through regulating key factors.
Ecosystem engineers contribute to ecosystem functioning by regulating key environmental attributes, such as habitat availability and sediment biogeochemistry.
The dramatic developmental defects in the cardiovascular, digestive, and respiratory tract support a major role for retinoic acid (RA) signaling in regulating key events during organogenesis.
Considering its association in regulating key β cell genes, PDX1 could be a pharmacological target for β-cell defects in T2DM[40].
The hormones that regulate the hypothalamic circuits that control essential functions, such as reproduction and energy homeostasis, also specify brain architecture by regulating key developmental events.
To counteract virally-induced changes in the cellular metabolic profile, the interferon-regulated antiviral response restricts viral access to key metabolites by altering cellular metabolism, mediated through induction of specific microRNAs regulating key lipid biosynthetic processes.
Clarification of the role of mitochondria in regulating key cellular processes including metabolic flux, autophagy, and apoptosis will drive the development of novel therapeutic strategies for maintaining mitochondrial quality and improving human health.
Here we report the identification of SlMX1 encoding a MIXTA-like MYB transcription factor in tomato that simultaneously modulates drought resistance and metabolic processes through regulating key structural and regulatory genes of the corresponding pathways.
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Perturbing plants by mis-regulating key genes/enzymes integral to major cell wall pathways can provide both rich insights into cell wall development and architecture, and concurrently provide significant opportunities for improved lignocellulose utilization.
Simultaneously, supplies may be bolstered by up-regulating key genes involved in import/utilization of primary and secondary carbon substrates and presumably recycling cellular components through autophagy.
Previous work from our group has demonstrated that PROK1 has an important role in early pregnancy by up-regulating key genes involved in implantation and early placentation (Evans et al., 2008, 2009; Cook et al., 2010).
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