Sentence examples for regulating its activity from inspiring English sources
However, the subcellular localization and phosphorylation state of the protein are critical in regulating its activity, and it would, therefore, be problematic to assess these changes in clinical samples.
However, whilst −7 enhanced luciferase expression under the control of the SV40 promoter, it was not capable of enhancing reporter expression under the control of the SCL pro1a, suggesting that the local chromatin environment may be important in regulating its activity in vivo or that it regulates SCL activity but not through enhancement of SCL pro1a.
It acts as a SAZ-associated structure, presumably regulating its activity, as a sensory structure as well as a hindgut sphincter.
Our data reveal a pro-survival role for Ras in activated primary T cells and describe a new methodology for regulating its activity.
Beyond that, nearly everyone agrees that online betting may be unstoppable because of the reach of the Internet and the difficulty in regulating its activity.
It has even been argued that the axial position ligand influences the oxidation potential of the enzyme, which possibly provides the mechanism for regulating its activity (Fig. 1) (Claus 2004; Kumar et al. 2003; Enguita 2011; Garavaglia et al. 2004).
SREBP (sterol regulatory element binding protein) is a transcription factor that regulates expression of numerous cholesterol synthesizing genes, and SCAP (SREBP cleavage activating protein) regulates its activity.
Mitotic p34cdc2 kinase that phosphorylates Ser-55 (Chou et al., 1990) could be involved, but it is unknown whether PAK1 kinase regulates its activity.
Although the signal is necessary for endocytosis, it has been unclear whether α-factor binding regulates its activity.
It is reported that SIRT1 binds HIF1 α and regulates its activity through direct deacetylation.
OTULIN is subject to phosphorylation, acetylation, and ubiquitination in cells, and it will be interesting to study whether these modifications regulate its activity or function.
