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Exact(3)
In addition, SIK is a direct transcriptional target of TGF-β signaling, and therefore it functions as a negative regulating feedback mechanism to limit TGF-β signaling [ 38].
Thus, there is a complicated regulating feedback loop between miRNA and chemo-resistance in cancers.
Furthermore, we found that K-Ras, c-Met and endogenous protein phosphatase activity are crucial in regulating feedback between the PI3K/Akt/mTORC1 pathway and the MEK/ERK pathway.
Similar(57)
Thus, the germline may also regulate feedback circuits to dampen sex-biased expression.
In principle, inhibitory plasticity mechanisms in mature cortex could regulate feedback inhibition at the level of each disynaptic circuit (Kullmann et al. 2012).
Prolactin interacts with its receptors to trigger paracrine signalling mechanisms through a highly regulated feedback mechanism involving JAK/STAT and map kinase activity, as well as other downstream targets, which in turn regulate proliferation and cell differentiation [ 14].
Moreover, it has become increasingly clear that miRNAs are integral elements in a number of crucial gene expression networks, acting in tightly regulated feedback loops that are often disrupted in cancer.
Using steroids remains controversial, which might be beneficial for regulating negative feedback of nervous and immune system.
They suggest that future research should address the effects of self-regulating feedback.
3) It is also not strictly correct to say that exchange of metabolites/cooperation does not happen in yeast, since the papers by Shou and Murray labs (cited in this paper as well) do generate a synthetic cross-feeding colony, except that these authors had to down-regulate feedback mechanisms involved in amino acid metabolism.
For example, one participant, who received SMA-PHC feedback, 'imagined numbers' in order to up-regulate the feedback signal and 'relaxed' or 'imagined dark colors' in order to down-regulate the feedback signal.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com