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Cell rigidity was weakened by down regulating expressions of ten genes in the cell wall synthesis pathway using CRISPRi, leading to elastic cells with more spaces for PHB accumulation.
These results strongly support the hypothesis that AMPK- α1 is critically required for TLR4-mediated signaling, thus leading to activation of NF-κB and AP-1, and thereby regulating expressions of NF-κB-dependent genes.
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CAMTA1 probably regulate drought recovery by regulating expression of AP2-EREBP transcription factors and Abscisic acid response.
Whether mTOR signalling also has a role in regulating expression of positive transcription regulators is not yet known.
NrrA also regulates glycogen catabolism in Anabaena sp. by directly regulating expression of glgP gene encoding glycogen phosphlylase and sigE gene encoding a group 2 σ factor of RNA polymerase [97].
By regulating expression and/or activity of pRB, A-type lamins can regulate both gene expression and cellular proliferation.
The down regulation of miR-206 could lead to cancer progression by up regulating expression of cyclin D2 [ 102].
The NF-κB family of transcription factors plays indispensable roles in regulating expression of many SASP components.
Transcription factors play vital roles in plant adaptation to stresses by regulating expression of a great deal of target genes.
Thus, the hypothalamic centers responsible for regulating expression of estrus and secretion of LH responded differently to estradiol-17β.
MiRNAs are recognized as critical links in cellular pathways and carcinogenesis, regulating expression of genes in a wide range of pathways critical for cancer development and progression.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com