It was proposed that p53-NTD can be involved in interdependent interaction with the C-terminus to regulate defined function of p53 [33].
Alternatively, a variety of proteins are known to regulate defined subsets of miRNA genes (e.g. Trabucchi et al., 2009); hence, training-related changes in one or more of such proteins might also affect miRNA pairwise correlations.
Comparison of gene expression between 37 advanced-stage serous ovarian carcinomas and normal ovarian surface epithelium cytobrushings revealed that BCoR-L1 was not one of 1,191 genes that were significantly differentially regulated (defined as greater than or equal to 1.5-fold change in expression).
Given the role of Dis3 in regulating a defined subset of the S2 cell transcriptome, we hypothesized that Dis3 depletion affects fly development by perturbing either the expression, processing, and/or turnover of vital developmental transcripts.
SPRINT is stopped when the patient is adequately self-regulating, defined as 6 or more hours (three 2-hourly measurements) in the 4.0 to 6.0 mmol/L band with over 80% of the goal feed rate and a maximum of 2 U/hour of insulin [ 27, 42].
Central to well-being is the ability to regulate emotions, defined as the automatic and intentional means by which people influence the emotions they have, when they are experienced, and how they are experienced and expressed (Gross, 1989).
Our data showed that both reporter genes could be regulated at defined and quantitative levels.
These results unravel the patterns of DNA demethylation by AZA and DAC and suggest that drug-induced demethylation is regulated by defined molecular mechanisms.
A molecular function map of EWS-FLI1 target genes was constructed by annotating the stringent set of EWS-FLI1 regulated genes defined above (GS1) using data bases of gene-function relationships.
In this study, we examine the potential of mechanical stimuli to regulate classically defined canonical and non-canonical signaling pathways in C3H10T1/2 murine MSCs by investigating the induction of β-catenin translocation and expression of Wnt associated proteins with fluid flow.
