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In principle, hyperarcs can connect an arbitrary number of start nodes (regulating components) with an arbitrary number of end notes (regulated components).
48 In summary, these data expand the role for SOX9 in regulating components of the ECM and begin to provide insight into its regulation by signaling pathways linked to fibrosis and related pathologies in the liver and other sites, such as the skin, kidney, lung, and major blood vessels.
Unlike a conventional watch's Incabloc shock protection system, which only protects the escapement from external shocks, the ADAS protects the movement in its entirety, not just its regulating components.
Both miR-146a and miR-155 have also been implicated in the development of rheumatoid arthritis, possibly by regulating components of the inflammatory response [16], [17].
Since B cell receptor signaling is involved in B cell development, activation and differentiation [25], oncogenic FLT3 might provides proliferative and survival signal for B cells by regulating components of B cell receptor signaling.
IAPs are a part of complex signaling network, regulating components responsible for a diverse array of migration phenotypes.
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LHY is a core regulating component of the A. thaliana clock, and it has been shown to be induced before dusk and has a peak of expression at dawn (Schaffer et al., 1998).
Therefore, the object of this review is to discuss the effects of exercise and cytokines on sleep, and the relation between these two sleep-regulating components, raising the hypothesis that the alterations in sleep promoted by exercise are mediated by cytokines, which, by increasing the nREM sleep phase, would stimulate the regenerating characteristics of sleep.
For instance, murine herpesvirus infections have been shown to provide protection from infection with other pathogens in mice by up-regulating components of the immune system [ 23].
The UPR attempts to alleviate ER stress by (i) decreasing protein synthesis, (ii) increasing the size of the ER, (iii) increasing the synthesis of ER chaperones and (iv) up-regulating components of the ER-associated degradation pathway.
The HIF- β/ARNT subunit is constitutively expressed and involved in a number of non-hypoxia-related processes, whereas the α-subunit is the hypoxia-regulating component (Carmeliet et al, 1998; Talks et al, 2000).
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