Cytokinin oxidase regulates the levels of cytokinin in plants by degrading it irreversibly [35].
We report here a novel mechanism that regulates the levels of Swe1.
We examine whether the A1R agonist also regulates the levels of the A2AR in vivo.
ß-catenin signaling also regulates the levels of Bmp4 and Fgfr2b expression in distal lung epithelium [4].
Apc is a gatekeeper that regulates the levels of β-catenin [22], a transcription factor that has Matrix metalloproteinase-7 [23] among its target genes.
Here, we provide evidence that in concert with H6PDH, 11β-HSD1 also regulates the levels of 7α-hydroxy-, 7β-hydroxy and 7keto-neurosteroids derived from DHEA and pregnenolone (Figure 1 and 5).
The results that we have presented here provide the first evidence that Akt interacts with, and regulates the levels of, Bcl-w, moving the balance of the Bcl-2 family toward anti-apoptotic members.
In contrast, Ubqn regulates the levels of APP: loss of ubqn function leads to a decrease in the steady state levels of APP, while increased ubqn expression results in an increase in APP levels.
These data demonstrate that T cell costimulation by CD46 but also by CD28 regulates the levels of expression of CD46 cytoplasmic tails, and suggest a crosstalk between these two costimulatory molecules.
In C. elegans, RNF-5 localizes to the dense bodies and the M-line of the body wall muscles, where it regulates the levels of the LIM domain protein UNC-95.
In mammalian cells, Nampt, which is the functional homologue of Pnc1p [41] [42], regulates the levels of mitochondrial NAD+, the activity of mitochondrial sirtuins and promotes cell survival under genotoxic stress [42].
