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To test whether mTOR regulates the effects of ND on the CMZ, we first immunostained for phospho-Ribosomal protein S6 (pS6), the cardinal marker of mTOR activity.
In another study, they found that low bacteria/DC (dendritic cells) ratio better regulates the effects on DCs in vitro, suggesting that different intracellular signaling pathways become activated when bacteria are present at high doses [ 52].
Furthermore, experiments with two other colorectal cancer cell lines (HCT-116 p53+/+ and HCT-116 p53−/−) revealed that p53 tumor suppressor protein negatively regulates the effects of p65 in BITC signaling.
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In this study we determined whether the stage of development of engineered cartilaginous constructs (expanded adult human articular chondrocytes/Polyactive foams) regulates the effect of dynamic compression on glycosaminoglycan (GAG) metabolism.
While the former affects NCR gene expression via Gln3/Gat1 activation, the latter regulates the effect of the TOR pathway on RP gene expression and Msn2/4 activation.
More interesting are the insights along the way and where Hitchings ends up: "the ability to evaluate and regulate the effects we have on other people is part of a fine awareness of our selves.
These results suggest that mTOR could negatively regulate the effects of LPS on the NF-κB and MAPK pathways.
To concluded, topography regulated the effects of fire on soil carbon fluxes and might control the post-fire soil carbon flux feedbacks to climate warming.
These results highlight the need to include measurements of changes in RH alongside measurements of FN in non-disturbed ecosystems to interpret the processes regulating the effects of management practices on long-term changes in soil organic carbon stocks.
Paired-end transcriptome sequencing identified unique patterns of gene expression in breast cancer stem cells compared to other breast cancer cell types that may regulate the effects of oncogenes and tumor suppressor genes [37].
In this Perspective, we synthesize past and present observations in the field of epigenetics to propose a model in which the epigenome can modulate cellular plasticity in development and disease by regulating the effects of noise.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com