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miRNAs are small non-coding RNAs that regulate sequence specific gene expression.
Overall, we postulate two activities that may function simultaneously to generate and regulate sequence diversity among the cluster of Sp185/333 genes.
Finally, the effects of concerted evolution and gene conversion on AAT gene sequences, both within and between loci, were examined for their potential to introduce artefact into phylogenetic reconstruction and to regulate sequence diversity.
All sequences regulated by LPS/INFγ/APC with a calculated fold change of more than 2.0 (p<0.01) were subjected to one-way ANOVA factorial analysis, compared with the significantly regulated sequences (fold change >2, p value<0.01) by LPS/INFγ.
This observation identifies a previously unrecognized role for hTERT Q169 in regulating sequence-specific interactions between the protein's N-terminus and ssDNA primers in vitro.
Functional annotation of consensus sequences was performed to define the differentially regulated sequences more precisely.
One can see that there are two major differences between p-value distributions in really regulated sequences and in the random sequence.
Eukaryotes have subsequently taken advantage of their expanded genomes by selectively regulating sequences provided by TEs, as envisioned in many earlier scenarios.
The most significantly enriched GO term for High-TS Genes was for "direct ligand regulated sequence-specific DNA binding transcription factor activity" (corrected p-value = 0.025).
These files present data regarding best hits in GenBank, annotation of the differentially regulated sequences, E-values, Gene Ontology and other useful information (where available).
The p53 protein acts as a highly regulated sequence-specific DNA-binding protein that in response to a wide variety of stress signals undergoes post-translational stabilisation and then acts as a master transcriptional regulator to induce the expression of many target genes.
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