Protein expression could be regulated precisely by changing the combination of genetic codes in both mammalian cell and engineered bacterial cells (Brule and Grayhack 2017; Wang et al. 2016).
However, when, where, what and how much a gene is expressed are regulated precisely and dynamically at multiple levels, including at transcription, mRNA maturation, alternative splicing, and translation levels.
It is for the first time that gas and water production of CBM wells are automatically regulated precisely and automatic CBM production modes are adopted with the linkage control of gas and water production.
And therefore, the fourth and final step is to recognize that drugs must be regulated precisely because they are risky.
An important function of the niche is to regulate precisely the balance between self-renewal and differentiation in order to maintain optimal organ function at all times.
The permeability of the mitochondrial membrane is regulated precisely by the Bcl-2 family proteins.
Notch activity needs to be regulated precisely, and aberrant Notch activity is associated with a number of human diseases including cancers and congenital syndromes.
MMPs are regulated precisely during synthesis and secretion, at the time of activation of the pro-enzyme and/or by localisation, clearance and inhibition of the active enzyme (Ra and Parks, 2007).
The position of the enamel knots are therefore supposed to regulate precisely the shape of the epithelium-mesenchyme boundary through reiteration of pro- and anti-proliferation signals in mammals [ 10, 20, 21].
Whilst microtubule number and length appear to be regulated precisely in the fission yeast spindle, the critical force of the longer spindles, at around 10 pN, is relatively small compared with other intracellular forces.
