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The former, a paralog of the pair-rule gene engrailed, is a transcription factor that is expressed in neuroectodermic cells [13], while mastermind is a key component of the Notch signaling pathway, which determines cell fate and regulates pattern formation.
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In early Drosophila embryos, the transcription factor Dorsal regulates patterns of gene expression and cell fate specification along the dorsal ventral axis.
GIK is an AT-hook DNA-binding chromatin modifier and regulates patterning and differentiation of reproductive organs in Arabidopsis.
hh is a segment polarity gene (Nüsslein-Volhard and Wieschaus, 1980) that regulates patterning within each segment of the Drosophila embryo.
The importance of ANB as a signaling center that regulates patterning of the rostral forebrain rudiment has been studied thoroughly in zebrafish and mice (Cavodeassi and Houart, 2012; Houart et al., 2002; Houart et al., 1998).
Layered patterns are important because they form a record of the state of internal and external factors that regulate pattern formation in these geological and biological systems.
The homeobox superfamily is comprised of hundreds of transcription factors known to regulate pattern formation in early development, although roles for some members in adult tissues as well as in oncogenesis have been described [15].
2, 23 A similar, highly regulated pattern of development is recapitulated in many vertebrate species including mice, rats, and rabbits.
The laminin alpha-5 chain, however, is expressed by both epithelial and stromal cells in a developmentally regulated pattern.
Bioelectric signals (resting transmembrane voltage potential gradients in all cells) underlie an important and broadly conserved set of control mechanisms that regulate pattern formation.
This suggests that Tjp1a and connexins do not act in a linear pathway to regulate pattern formation, but most likely work through different mechanisms.
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