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Platelet-derived CXCL12 differentially regulates differentiation of CD34+-progenitor cells into a macrophage and foam cell phenotype.
HDAC4, which encodes a histone deacetylase that represses transcription and regulates differentiation, was down-regulated in our experiments [ 43].
BMP regulates differentiation of various types of cells, but its main target is the regulation of osteoblast differentiation.
To test whether bone morphogenetic protein 4 (BMP4) directly regulates differentiation of adult mouse ovary-derived oogonial stem cells (OSCs) in vitro.
Bone morphogenetic protein 4 (BMP4) is critical for lung morphogenesis and regulates differentiation of the airway epithelium during development, although its mechanism of action is unknown.
Mechanistically, SLUG regulates differentiation and cellular plasticity by recruiting the chromatin modifier lysine-specific demethylase 1 (LSD1) to promoters of lineage-specific genes to repress transcription.
To investigate this problem, we compared the Bacillus subtilis circuit that regulates differentiation into the competence state to an engineered circuit with an alternative architecture (SynEx) in silico and in vivo.
Notch receptor regulates differentiation of almost all tissues and organs during animal development.
One important factor that regulates differentiation on the cellular level is Ca2+.
Trk A is a tyrosine kinase receptor that is stimulated by NGF, and prevents apoptosis and regulates differentiation in neurons [23].
Activin, a member of the transforming growth factor-β superfamily, is an endocrine hormone that regulates differentiation and proliferation of a wide variety of cells.
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