Sentence examples for regulates accessibility to from inspiring English sources

Furthermore the sequestration of PIP2 by MARCKS regulates accessibility to this important signaling substrate [11].

Epigenetic changes involve the physical remodeling of chromatin structure that in turn regulates accessibility to transcription factors.

This organization not only condenses the genome to fit within the confines of the nucleus, but also provides a platform for a cell to regulate accessibility to different gene sequences.

As a result of the architecture and the properties of the combined structure elements a functional macromolecule is obtained that might regulate accessibility to a central shape persistent macrocycle via reversible brush-coil transitions.

It is presumed that chromatin compaction can influence transcriptional activities by regulating accessibility to transcription factors and DNA interactions [3] [5].

Interestingly, MARCKS family members regulate accessibility to PIP2 and any reduction in their expression could promote adherens junction formation through this pathway.

These findings along with studies of the competition between E. coli SSB and the RecA recombinase protein demonstrate how SSB bound in its different modes might regulate accessibility to ssDNA of other genome maintenance proteins.

The state of CpG methylation regulates and stabilizes chromatin structure, and possibly regulates accessibility of these DNA regions to the transcription machinery [ 2].

We propose a helix-to-loop conformational switch in the helices flanking the inner active-site loop that regulates accessibility of the active site.

Although both remodeling and histone modifications are essential to open up the chromatin and, thus, regulate accessibility of RNA polymerase to become engaged in active transcription, how recruitment of remodelers and active epigenetic marks is temporally orchestrated and preserved is not fully understood.

Specific inherited histone modifications and the reading effectors could induce the specific spatial and temporal gene expression by regulating accessibility of the DNA to transcriptional machinery during development and differentiation [8].