Sentence examples for regulated turnover from inspiring English sources

The proteins involved in cell migration undergo spatiotemporally regulated turnover and need to be folded rapidly to function properly.

Once thought to be solitary and rigidly structured, mitochondria are now appreciated to constitute a population of organelles that migrate throughout the cell, fuse and divide, and undergo regulated turnover.

Further support of a dynamic, rather than a static, role of Crk Y221 phosphorylation came from studies showing that Y221F Crk II expression prevents regulated turnover of Crk/Abl/p130Cas or Crk/Abl/paxillin complexes, leading to impaired adhesion and migration [ 173].

Additionally, Parkin is recruited to mitochondria where it is thought to regulate turnover of damaged mitochondria.

After H2O2 exposure under aerobic conditions, ArcA was found to regulate turnover of reduced glutathione (GSH).

This phenotype was also seen when endocytosis was inhibited suggesting that Fra signaling may regulate turnover of the βPS/αPS1 Integrin.

We also show that spartin recruits AIP4 to lipid droplets and promotes ubiquitination of lipid droplet-associated protein, adipophilin, which regulates turnover of lipid droplets.

CRLs are multi-subunit complexes regulating turnover of many proteins involved in cell growth and survival and members of this family have been described to be potential oncogenes.

Notably, recent studies have found that NEDD8 dictates binding of a subset of CRLs to UBXN7/p97 complexes to regulate turnover of their ubiquitylation substrates.

Attachment of Ub or more frequently of polyUb chains to proteins regulates turnover, localization, complex assembly or activity of the substrate.

NHS may regulate turnover, displace or compete for the complex and negatively regulate WAVE function, which would be consistent with the observation that the absence of NHS leads to excessive cell spreading due to overactive WAVE complex activity.