This maximises the distinction between Wnt-ON and Notch-ON responses which is vital foresponsesg regulated transitions betwhichcell states wishin a lineage.
Further studies are required to understand the molecular mechanisms regulating transition from "microcalcification" to "macrocalcification", thus allowing to design therapeutic strategies which favor this adaptive process, in order to limit the adverse effects of established atherosclerotic calcification.
This indicates a possible role for VEGF-A in the mechanisms regulating transition to SPMS.
The expression of cyclin A and CDK2, which regulates transition from S or M phase, was decreased with the treatment of thioridazine.
Akt regulates transition through the cell cycle by inhibiting the transcriptional activity of FOXO, which has a number of cell cycle regulatory proteins as its targets.
Some of these phenotypes are new and the mechanism by which ANGUSTIFOLIA regulates transition processes from the vegetative to the reproductive phase is still unknown.
The mechanism by which CURVY1 regulates transition processes from vegetative to reproductive phase needs to be investigated in agronomically important crops.
The G1-S and intra-S-phase checkpoints regulate transition into, and progression through S phase in response to DNA-damage, while the G2-M checkpoint regulates entry into mitosis [ 26].
Although SEs have been shown to regulate cell identity genes in resting steady state, the role of SEs in regulating transition states such as cell differentiation and activation is not well appreciated.
CDKA genes are constitutively expressed throughout the cell cycle, and they interact with several cyclin proteins to regulate transition through phases of the cell cycle, including the germ cell cycle in Arabidopsis [ 75].
