Sentence examples for regulated trail from inspiring English sources

Collectively, these results demonstrate that NFATc1 regulated Sp1 protein binding to the TRAIL promoter and thus, regulated TRAIL expression.

Hence regulated TRAIL gene expression is critical in cancer gene therapy to prevent toxicity and optimize therapeutic outcomes.

In CML patients it was shown by De Carvalho et al (2011) that PRAME regulated TRAIL, and upon PRAME knock down it was possible to induce TRAIL expression, and thereby increase imatinib sensitivity.

To validate type I IFNs were the diffusible factors that regulated TRAIL, we transferred supernatant from HIV-1-infected MDM to uninfected MDM.

As shown in Fig. 3D, HIV-1 PV-infection down-regulated c-FLIP expression in the cells but did not affect the expression of Bcl-2 family members tested, suggesting that down-regulated TRAIL decoy receptors and c-FLIP expression facilitate TRAIL-induced apoptosis in HIV-1 PV-infected MDM.

Regulator-regulated gene associations.

Among the TRAIL-regulated transcription factors were TEAD1 and Egr-1.

Geminare CEO Joshua Geist says he has invested in making sure his service can meet the security and audit trail requirements of regulated industries like financial services, even while enjoying the economies associated with cloud computing.

Furthermore, consideration should be given to this newly identified pathway with respect to possible negative side effects of TRAIL in cancer therapy and TRAIL-regulated processes in the immune system.

Three up-regulated anti-viral genes (OAS2, CXCL10, TRAIL) and a gene (C4bp) that was down-regulated specifically in the MRNL were selected for real-time PCR studies.

As a result of successful antiretroviral therapy TRAIL is down-regulated, and there are fewer TRAIL-sensitive cells.