Sentence examples for regulated to elicit from inspiring English sources
On the other hand, overexpression of SIRT1 has been reported to negatively regulate Tip60-mediated acetylation of H2AX, an event finely regulated to elicit proper DNA damage response (Yamagata and Kitabayashi, 2009).
These suggest that under the normal condition, calpains should be tightly regulated to elicit proper functions at the NMJ; further studies will clarify which calpains, conventional and/or muscle-specific calpains, are critical to the phenomenon.
Gadd45α is known to be upregulated in response to a variety of cell stresses in order to elicit cell cycle arrest at the G2-M transition and to regulate the apoptotic response.
The lower or even missing capability of TNFR2 to trigger the classical NF κB pathway corresponds to former reports demonstrating that TNFR1 is superior to TNFR2 in activation of this response and that the latter depends on the presence of the highly regulated TRAF1 protein to elicit an optimal response.
The canonical mechanistic pathway from IPA was used to identify plausible regulatory factors that are co-regulated by STAT1 to elicit the observed changes in the level of expression of target genes.
Patterns of methylation at lysine 4 and 27 of histone H3 have been associated with gene activation and repression that are developmentally regulated and are thought to elicit the coordination of lineage specific gene expression programs [37].
In conclusion, this study demonstrated that PC in TNBC cells (i) inhibits the proliferation (ii) promotes change in the Bcl-2/Bax ratio (iii) inhibits metastasis via actin cytoskeleton disruption (iv) suppresses angiogenesis and (v) down-regulates MAPK signaling pathways to elicit cell death (Fig. 8).
In this study, DNA vaccines were constructed to express virally regulated human immunodeficiency virus-like particles (VLP) to elicit broad-spectrum immune responses to multiple HIV-1 antigens.
Thus, FGF19 acts through multiple receptor pathways to elicit pleiotropic effects in regulating nutrient metabolism and cell proliferation.
Upon the binding of EphrinA1, the EphA2 receptor becomes tyrosine phosphorylated and interacts with several proteins to elicit downstream signaling, which regulate cell adhesion, proliferation, migration, and angiogenesis [ 60].
In fact, mutations at conserved threonine residues that antagonistically regulate kinase activation affect similarly the NIK capacity to elicit an antiviral response and to mediate a phosphorylation-dependent nuclear relocalization of the rpL10 downstream component.
