Both direct and indirect evidence suggests that G-quadruplexes are also present in eukaryotic cells and that formation of this structure must be tightly regulated to allow DNA replication and cell division (for a review, see [4]).
These data show that the levels of N-cadherin must be correctly regulated in order to allow for proper NC migration.
Through intrinsic and extrinsic factors, adult neurogenesis is tightly regulated in order to allow for the maintenance and self-renewal of the stem cell pool and the generation of fully functional neurons.
Although many transcription factors are regulated at a transcriptional level, requiring de n ovo protein synthesis, HIF-α is primarily regulated post-translationally to allow for a rapid response to decreasing oxygen levels (Berra et al., 2001; Moroz et al., 2009; Wang et al., 1995).
We discuss a model in which CES is regulated by BIN2 action, to allow for a control of BR biosynthesis and also of other BR responses.
Longhurst told VICE that recovery homes should be regulated through the health authority, to allow for better tracking and accountability.
Cluster Score Nodes Edges miRNAs Cluster Score Nodes Edges miRNAs LPS-induced signalling must be tightly regulated to avoid excessive inflammation and to allow for tissue repair and the return to homeostasis after infection and tissue injury.
Mounting evidence exists that low-frequency-usage codons within a coding sequence can provide the genetic instruction that regulates the rate of protein synthesis to allow for some secondary and tertiary structure formation by the nascent polypeptide [ 2, 46].
In agreement with the latter finding, the synthesis of many mammalian proteins associated with the translation apparatus is regulated at the translational level [ 25] to allow for fast responses to changes in physiological conditions.
Type I circuits, in which the miRNA and its target are regulated together would allow for modulation of protein translation, maintenance of cellular homeostasis, or modulation of changes in local protein concentrations.
