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Normally, mitochondrial biogenesis and function are dynamically regulated to adapt to the energetic and metabolic demands in response to physiological signals.
Redox homeostasis is crucial for the diverse functions of mitochondria and so it is expected that the MIA40 pathway is regulated to adapt to redox changes.
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These reactions mark the key nodes in the metabolism network that must be appropriately regulated in order to adapt in response to the available energy/carbon source.
RNRs must be tightly regulated to achieve the dNTPs levels needed to rapidly adapt to any environmental changes.
Translation is tightly regulated in order for organisms to adapt quickly to environmental stresses, such as oxidative and heat stress [ 10, 66].
"We are a very cautious, very regulated profession, which tends to adapt to change very slowly," says Hunter.
Self-directness is the ability to regulate and adapt behavior to the demands of a situation in order to achieve personally chosen goals and values.
This may be the mechanism by which miRn6 regulates the expression of TBLP to adapt to drought stress.
Our model suggests that one benefit of regulating acyl-chain composition is to adapt membrane flexibility to a required curvature.
We have previously speculated that these increased activities reflect an attempt by the tissue to adapt to regulate increased H2O2 (5) and the current data are compatible with this possibility.
Since HIF originally functions as master regulator of oxygen homeostasis in all metazoan species, HIF also regulates glucose and energy metabolism to adapt to reduced oxygen availability in hypoxia-susceptible diabetic kidneys.
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