Sentence examples for regulated through specific from inspiring English sources

Bioactive peptides are regulated through specific peptidases that hydrolyze them.

This expansion may have to do with the specialized developmental programs that potentially are regulated through specific MYBs, including but not limited to the lignin synthesis and deposition that orchestrates the stone hardening process and the flavonoid synthesis that is important to fruit color, nutritive properties and disease resistance [ 29, 69- 71].

These observations suggest the CYP3A4 is regulated through tissue specific epigenetic regulation in normal tissue.

Thus, our data indicate that monoallelic expression of the IGF2BP1 gene is regulated through allele-specific transcriptional elongation prior to SNP site rs4794017, located approximately 600 bp downstream of the first intron splice site.

These effects are mediated at a molecular level by the nuclear glucocorticoid receptor (GR) [ 4], but recent studies have indicated that GR signalling is rheostatically regulated through tissue-specific metabolism of GR ligands.

The mechanism by which indirect activation occurs is unclear; however, the analysis of KRAB/FLI-1 expressing ES/PNET cell lines will enable the identification of genes specifically regulated through FLI-1-specific DNA binding in ES/PNET.

We hypothesized that this set of genes would be regulated through effects on specific transcription factors and, therefore, be suitable for further study aimed at identifying transcriptional control mechanisms downstream from mTORC1.

Furthermore, Src/ezrin co-operativity is regulated through phosphorylation of specific tyrosines (Y145 and Y447) on ezrin by Src [ 5, 24].

This finding was somewhat unexpected since cellular activity in response to its microenvironment stimuli is dynamically regulated through transient and specific changes in gene expression.

Interestingly, studies from other groups have demonstrated that the activity of SHP-1 can, in turn, be regulated through phosphorylation at specific Ser/Thr residues [ 55].

Recently it has additionally been demonstrated that Nrf2 itself is a potential direct target of oxidation, and that its nuclear distribution and consequent activity can be regulated through modification of specific cysteine residues by oxidation [30].