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In human WPMY1 cells, 2728 genes (84%) were also regulated through either a type I or type II response [ 13].
The sirtuin family of proteins also regulate some aspects of aging and it has been postulated that the life-extension benefits of CR are regulated through either the TOR or sirtuin pathways, or possibly both [11], [12].
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This suggests that genes, which fail to be repressed by prednisolone in GRdim mice, are either regulated through GR binding to negative GRE elements (nGREs) or indirectly regulated via other GR target genes.
Most mammalian mRNAs are targeted by miRNAs and post-transcriptionally regulated through the presence of either conserved or non-conserved miRNA sites in their 3′ UTR [ 9].
Finally, a comparison between PICH isolated from S- or M-phase arrested cells revealed no differences in ATPase activity, arguing that PICH activity is either not regulated through the cell cycle or that regulation occurs through a mechanism that does not resist immunoprecipitation.
This analysis showed that many of the miRNAs were regulated through each other either directly or indirectly, and were also regulated by several target genes.
We observed that many miRNAs are regulated through each other either directly or indirectly, and many are indirectly regulated by the same signaling molecules, for example, beta estradiol.
Drug consumption can be influenced and regulated through different monetary incentives, regulation, schooling and exchange of information.
This finding indicates that PhaPR1 might be regulated through machinery similar to that regulating other well-known PR1 proteins.
Rather, they were regulated through international agreements or even self-regulation arrangements between private actors.
Moreover, absent regulation by legislation, AI could wind up regulated through case law from litigation.
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