Sentence examples for regulated stability from inspiring English sources

The cell preserves its normal functional state and reaction to microenvironment stimuli, so that if the therapeutic protein is not needed at a particular period in time, the transfected cell may decrease the mRNA of the transgene by intracellular posttranscriptional mechanism regulated stability and the half-life of mRNA and thereby prevent protein production [ 151].

shRNAs are artificial analogs of endogenous miRNAs, the vast class of small non-coding RNA molecules that regulate stability and translation of their target mRNAs.

Future studies are needed to elucidate the mechanism by which CSB regulates stability of triplet repeats.

As a class of small noncoding RNAs, microRNAs (miRNAs) regulate stability or translation of mRNA transcripts.

RBPs with diverse RNA recognition motifs bind p21 mRNA, regulating stability of the transcript.

Among those, AREs regulate stability of the associated gene transcript by directing the binding of regulatory proteins.

This result was unexpected, since KHSRP has been shown to negatively regulate stability of its target mRNAs [ 71, 96].

MicroRNAs (miRNAs) are small noncoding RNAs that regulate stability and translational inhibition of target messenger RNAs (mRNAs).

It is likely that additional 3'UTR elements should regulate stability of the differentially expressed transcripts in Leishmania.

An intrinsic question is whether the stability of lncRNAs is regulated by identical or comparable mechanism that regulates stability of mRNAs in cleavage stage development.

Although PHD enzymes regulate stability of HIF and thereby induce cellular adaptations in response to hypoxia, it remains largely unknown how these enzymes are regulated.