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These data were the first to show that the properties of bone matrix are regulated, specifically through Runx2 pathway in P-AF group.
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It is therefore conceivable that ERK5 also features in the differential expression of the gonadotropin subunit genes, by regulating specifically FSHβ transcription through Nur77 and MEF2D.
We reported that the aromatase gene was regulated tissue-specifically through the alternative use of multiple exons 1 [ 20].
The mechanism by which indirect activation occurs is unclear; however, the analysis of KRAB/FLI-1 expressing ES/PNET cell lines will enable the identification of genes specifically regulated through FLI-1-specific DNA binding in ES/PNET.
The photoperiod regulates seasonal responses specifically through SCN control of nocturnal pineal melatonin secretion.
These data demonstrate that a variety of aspects of the breast cancer metastatic phenotype are specifically regulated through IRS-2.
In light of our interest in gene expression, specifically regulated by blue light through both cry1 and HFR1, introducing the concept of the interaction between genotype and blue light treatment can rule out non-specificity and provide a way to look at gene profiling without the interference from other blue light photoreceptors.
We developed low phytate rice by down regulating MIPS gene expression tissue specifically, through the use of seed specific promoter, Oleosin 18 (Ole18).
MicroRNAs (miRNA) are a class of small non-coding RNAs (approximately 21 nt long) that bind complementary sequences in target mRNAs to specifically regulate gene expression through either mRNA degradation or translational inhibition [ 4].
We demonstrate that the initial step in GagProPol processing can be specifically and reversibly regulated through oxidation of the cysteines of the embedded HIV-1 protease, and that this regulation differs in some ways from that of mature HIV-1 protease.
In addition, MT genes carry specifically adapted functions, which are tightly regulated through their expression as discrete isoforms [44].
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