Sentence examples for regulated pathology from inspiring English sources

Furthermore, androgen withdrawal has previously been shown to enhance expansion of Treg and naïve T-cell populations, leading to protection from disease in an EAE mouse model 37. Thus, this expansion of Treg in CSX mice is likely to reflect the enhanced requirement for regulated pathology following restoration of the Th2 immune response.

Most of the ion channel-modulating drugs that are currently on the market were developed without extensive knowledge of the molecular structure of ion channels, or an understanding of the full complexity of ion channel subtypes or knowledge of how ion channel expression is regulated during pathology.

Microglia are resident immunocompenent and phagocytic cells of central nervous system (CNS), which produce various cytokines and growth factors in response to injury and thereby regulate disease pathology.

Moreover, EVs secreted from the surrounding cells have also been reported to regulate tumor pathology [ 67].

Our findings shed light onto a novel mechanism regulating dendritic pathology, which may be relevant for neurodegenerative diseases including glaucoma.

Previous studies have demonstrated that IL-1 β is chronically upregulated in AD and believed to serve as a part of an inflammatory cycle that regulates AD pathology.

Through an increasingly finessed approach to genetic manipulation, we are gaining an ever more detailed picture of the cellular and subcellular processes that regulate hepatic pathology.

Therefore, the CCL20/CCR6 axis is thought to be an important local factor involved in regulating the pathology of allergic inflammation in patients with severe VKC.

IL-7 is also able to regulate joint pathology by T cell-driven immune activation in the absence of a clear inflammatory response.

Previous studies have demonstrated that IL-1 β is chronically upregulated in AD and believed to serve as a part of inflammatory cycle that regulates AD pathology.

Additional work that was published in parallel to our publication demonstrated the role of GSK-3 in regulating Aβ pathology, but suggested different mechanisms that involved either reduction in β-site APP cleaving enzyme-1, BACE1, expression or enhancement in APP processing via lysosome biogenesis.