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Since the amount/activity of transcription factors bound to the AP-1 motif are regulated partly through the extracellular signal-regulated kinases (ERK1/ERK2), we determined the effect of PD 098059, an inhibitor of ERK1/ERK2 activation, on the in vivo invasiveness of a human squamous cell carcinoma cell line (UM-SCC-1) derived from the oral cavity.
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In terms of "C Quantity," estimates suggest that between 0.5 and 5% of plant fixed C enters the rhizosphere through plants roots, but this flux of C into soils is regulated partly by the amount of root present, and partly by processes such as the amount of photosynthesis in the shoot [37].
This suggests that senescence-associated processes may be regulated partly by O-GlcNAc modifications.
eNOS expression in ECs seems to be regulated partly by HDAC-dependent mechanisms [ 147].
NOTCH1 is regulated partly by ubiquitination and degradation that involves FBXW7.
As E-cadherin is a substrate of Skp2 (Inuzuka et al, 2012), Skp2 regulated EMT partly through degradation of E-cadherin.
HMGB1 regulates autophagy partly through increasing transcriptional activities of JNK and ERK.
Salt intake regulates this cascade, partly through aldosterone (Chiga et al., 2008; Vallon et al., 2009).
These results suggest that zDia2 plays a role in regulating epiboly cell movements at least partly through regulating actin dynamics to form specific F-actin structures, which might affect protrusive activity, especially the membrane blebbing we previously observed, and other functions such as conducting actomyosin contractility at the marginal EVL at later epibolic stages [35].
Invasive capability is partly regulated through the ERK and Src pathway.
HGFIN is partly regulated by p53 through multiple binding sites within the 5' flanking region [ 12].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com