Sentence examples for regulated over time from inspiring English sources

Although Ta-miR021-1-5p was up- regulated over time while miR1852 was down-regulated, the degree to which their expression was altered was not as dramatic as had been demonstrated with high-throughput sequencing (Additional file 4, Table  1).

Fig. 4 Transcripts regulated over time of day in thyroid.

Fig. 5 Transcripts regulated over time of day in kidney cortex and medulla, and liver.

We have shown that neutrophils express a selected repertoire of microRNAs and that a small number of these are regulated over time as neutrophils begin to undergo senescence/spontaneous apoptosis.

To identify microRNAs that were regulated over time or upon treatment with GMCSF, only microRNAs that were expressed in at least 2 out of 3 donors at any one time point or treatment were selected for analysis.

Furthermore many of these cell type-specific changes in gene expression are also differentially regulated over time, with a large proportion of the genes that are over-expressed in DCs vs Mφs at 18 h also significantly induced in M. tuberculosis extracted from DCs at 18 h compared to 1 h post-infection (Figures 6B & 7A).

Mutant strains representing 26 of the most differentially regulated genes over time were selected from the BW25113 KEIO mutant collection [ 26] and analysed using microarrays as described below.

Genes related to cytotoxicity were differentially regulated but the gliotoxin biosynthesis genes were down regulated over the time course, while Aspf1 was up-regulated at 9 h and 12 h.

These results mean that autophagic flux was differentially regulated over the time period of 2DG treatment.

Thus, both core clock and clock-controlled gene expression is still temporally regulated over circadian time, albeit with reduced amplitude for some genes, in the SCNs of intact Six3-Cre Lhx1lox/lox mice.

In 2006, 230 full-time health inspectors were employed to regulate over 39,000 pharmacy outlets [ 16].