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In summary, differential expression of these defense-related genes indicates a developmentally regulated modulation of defense responses during ripening in Norton berry skin.
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Samples treated with oestradiol or fulvestrant were used as a positive control to show ER-regulated modulation of target genes in MCF7-X and TamR cells [ 3, 36].
cPLA2α activity can also be regulated by modulation of sphingolipids and cholesterol in CHO-2B cells [30].
Thus, insulin signalling can be negatively regulated through modulation of IRS concentrations in cells, via degradation of the proteins in the proteasomal pathway [ 18- 20].
The MMP-dependent release of cytochrome c and consequent caspase 9 activation are regulated by modulation of genes belonging to the Bcl-2 family.
DOI: http://dx.doi.org/10.7554/eLife.02407.002 Many steps throughout the transcription cycle of RNA polymerase II (Pol II) can be regulated, and modulation of any step has the potential to alter the timing and output of mRNA production.
All these findings re-confirm the in vitro results about the inhibitory effects of AST on tumor angiogenesis that are regulated by modulation of both mTOR and COX-2 signaling in colon cancer cells.
It is possible that prostasin activity is regulated by modulation of the ratio between HAI-1A and HAI-1B as it is not clear whether the two inhibitors have the same kinetic properties.
In conclusion, serotonin may regulate attentional modulation of early cortical stimulus processing.
Several transcription factors have been suggested to regulate phenotypic modulation of SMCs but the decisive mechanisms remain unknown.
However, very few studies have investigated the spinal mechanisms regulating the modulation of activity between muscles acting at different joints.
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