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Additional protein lipid, and lipid lipid interactions provide regulated modification of ER membrane phospholipid composition which are required to support the cooperative interactions required for selective transport.
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This potential activity of Not4 toward mRNA processing and export factors may regulate modification of their function through mono-ubiquitination or target them for degradation through poly-ubiquitination.
PmrA/B control only a subset of the genes that regulate modifications of the LPS, and pmrA mutants remain resistant to some antimicrobial peptides such as cathelicidin.
These researchers insightfully argued that "the in vivo proteolytic activity and the in vivo substrate specificity of the proteasome may be regulated by modification of its subunit composition during fly development" (Haass and Kloetzel, 1989).
Carrot growth and development may be regulated by modification of the genes involved in gibberellin biosynthesis, catabolism, and perception.
Our results suggest that the MAD2-mediated sensitivity to cisplatin may be regulated through modification of the MEK pathway.
In the case of TDG, which binds AP-sites very rigidly, dissociation is regulated by modification of a C-terminal lysine residue with small ubiquitin-like modifiers (SUMOs).
The PEEP was generated by a specific Automatic Pressure Limited valve (DIMAR, Mirandola, Italy), which can be externally regulated by modification of the internal lumen's flow resistance.
Recently it has additionally been demonstrated that Nrf2 itself is a potential direct target of oxidation, and that its nuclear distribution and consequent activity can be regulated through modification of specific cysteine residues by oxidation [30].
Elongation is also a critical phase of transcription that is highly regulated, and modification of the RNA Pol II carboxy-terminal domain is just one example of such regulation (Saunders et al. 2006; Egloff and Murphy 2008; Fuda et al. 2009).
Moreover, it has been established that viruses are capable of utilizing other pathways in order to regulate the modification of their own mRNAs and evade host immune system [ 88– 90].
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