Sentence examples for regulated initiation of from inspiring English sources

We focused on the region upstream of transcription start sites (-500 to -1) since this DNA segment contributed to formation of protein complexes that regulated initiation of mRNA synthesis [ 13].

This indicates that the oligo(A) tail is the site of a rate-limiting step in mRNA turnover, perhaps reflecting assembly of the surveillance machinery or regulated initiation of decay.

The effect was rapamycin-sensitive pointing to a role of the eukaryotic translation initiation factors eIF2α and eIF4E, which were shown to be decisive factors for regulated initiation of translation of a subset of mRNAs that have cis-regulatory small upstream open reading frames [ 18, 22, 33].

Webster, C. P. et al. The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy.

RhoA regulates initiation of invagination, but not convergent extension, during sea urchin gastrulation.

Wnt/β-catenin signaling regulates initiation of chondrocyte hypertrophy by inhibiting PTHrP signaling activity, but it does not regulate PTHrP expression.

In many cases, the regulation occurs at the level of transcription termination but a few of these elements also regulate initiation of translation (Figure 2).

Summer squirrels lack this inhibitor, which down-regulates initiation of translation and thus protein expression, in wintering animals during hibernation [46].

We propose that FLNs regulate initiation of cell migration such that below a certain FLN expression threshold initiation is reduced and the probability of observing it during the time-lapse recording is decreased.

Wnt/β-catenin signaling regulates initiation of chondrocyte hypertrophy by antagonizing PTHrP signaling, whereas it acts independently of PTHrP signaling in controlling the final maturation of hypertrophic chondrocytes (Fig. 4C).

Because the mTOR pathway is known to regulate initiation of autophagy, we examined Akt/mTOR signaling by determining the levels of phospho-Akt and phospho-S6 in the irradiated WT and caspase DKO MEF cells.