Sentence examples for regulated inactivation of from inspiring English sources

These data suggest that the localization of Sid1p-Cdc14p thethe SPB, and thus activation of the SIN, is linked to mitotic exit through regulated inactivation of Cdc2p kinase activity.

It is reasonable to envision that regulated inactivation of RAC/ROPs at the tube apex is crucial for locally modulating their activity while lateral inhibition ensures inactivation of those GTPases that are displaced to the apical flank as the apex migrates forward, ensuring that active signalling is restricted to the tip.

Yeast cell polarization may be more tightly regulated by inactivation of Cdc42 by GTPase activating proteins or by alternative methods of Cdc24 regulation, such as conformational changes or oligomerization.

CS is genetically regulated and inactivation of numerous genes including TOR (Target of Rapamycin) extends lifespan [ 2, 11- 23].

In conclusion, we have identified DUSP16 as a new epigenetically regulated gene inactivation of which seems specific to BL.

In RNAi-lines in which the histone deacetylases HDA6 and HDT1 are knocked down, the developmentally regulated condensation and inactivation of A. thaliana NORs is disrupted.

In conclusion, we have identified a specific member of the MiTF/TFE family of transcription factors, the oncogenic transcription factor TFE3, that was regulated by the inactivation of the FLCN tumor suppressor gene through induction of TFE3 nuclear localization.

In another study of 1,740 breast cancer patients, cyclin D1 expression was not tightly associated with proliferative genes that are regulated by the inactivation of CDK4 substrate RB [ 46].

Ras has been shown to regulate YAP via inactivation of LATS kinases (Reddy & Irvine, 2013).

BPA25 and BPA2500 significantly up-regulated the phosphorylation (inactivation) of Bad compared with control.

In mammals, parkin, PINK1, Bnip3 and Bnip3L have been shown to regulate mitophagy, and inactivation of the genes encoding these proteins leads to abnormal mitochondria (Fig. 2) (Bothe et al., 2000; Hara et al., 2006).