Sentence examples for regulated in large from inspiring English sources

The fact that substantially more genes were up regulated than down regulated in large healthy follicles, could indicate that activation rather than a reduction in additional pathways occurs as follicles enlarge.

Bad and Caspase-9 are thought to be key regulators of cellular apoptosis whose activity is regulated, in large part, by Akt phosphorylation [ 25, 40, 41].

A new pathway or molecule identified by IPA Upstream Regulator analyses is MGEA5 (meningioma expressed antigen 5) which was down regulated in large follicles.

Other interesting highly down regulated genes of various functions include the developmental genes: MEST (the most down regulated in large follicles, 28-fold), IHH (also Figure  5B) and MYC, and also JAKMIP1, which participates in cell polarisation.

The transcription of genomic information in eukaryotes is regulated in large part by chromatin.

Motility and metastasis are thought to be regulated, in large part, by the interaction of membrane proteins with cytoplasmic linker proteins and of these linker proteins, in turn, with actin.

While the mode of regulation of this suite of genes has been studied in the yeast, Saccharomyces cerevisiae, how this gene set is coordinately regulated in the larger and more complex metazoan genomes is not understood.

Required credentials are not specified and compensation and protected time are not regulated resulting in large discrepancies among institutions.

In at least some situations, gene dose is regulated in order to produce large amounts of product.

However, the numbers of genes regulated in these pathways were not as large when compared to the functional groups described in the previous sections.

Additionally, there was a subset of genes differentially expressed between populations that were concordantly regulated in both sexes, but to a larger extent in one sex than the other.