Sentence examples for regulated in a model of from inspiring English sources

In this study we demonstrate for the first time that the protein-tyrosine-phosphatase (PTP) DEP-1 is differentially regulated in a model of high-fat diet (HFD) induced obese mice, and that targeting DEP-1 leads to improvement of the metabolic phenotype.

In addition, miR-29 is down-regulated in a model of delayed onset of aging, the Ames dwarf mouse [ 42]. miR-29 was also found to be increased during spontaneous senescence in fibroblasts [ 17].

In the experiments, the thermal manikin was regulated in a dynamic mode using a model of human thermoregulation and was employed to evaluate the fulfillment of the thermal comfort criteria.

Neuropeptides like SP are up regulated in DSS model of experimental colitis, and there is increased expression of SP binding sites in UC and CD [9].

We expect that IMP-WFDR and other tools that allow biologists to analyze high-throughut data in the context of biological relationships will play a key role in identifying genes differentially regulated in key models of human physiology.

This work paves the way towards the systematic identification of GPCRs expressed and regulated in murine models of human pathologies, offering the potential to identify novel, drugable pharmacological targets for these pathologies.

MiR-142-3p is differentially regulated in various models of inflammation (Moschos et al, 2007; Recchiuti et al, in press) and regulates inflammatory mediators in cells of the immune system, including IL-6 (Huang et al, 2009; Sun et al, in press).

This suggests that these radiation-responsive genes mediate important brain-related functions independent of their potential role in the DNA damage response which is further exemplified by our observation that they are highly regulated in mouse models of Huntington disease (HD) and microcephaly.

We therefore explored whether MEFV expression was regulated in IBD experimental models of colitis and whether MEFV variants were associated with CD and/or UC susceptibility.

The only variable that is regulated in this model is the size of the stomatal aperture (the controlled parameter).

Determining such target set is important for fully understanding the role of various miRNAs and to model the networks they regulate in a condition of interest.