Sentence examples for regulated fusion of from inspiring English sources
Multinucleate muscle fibres form by the regulated fusion of myoblasts.
Regulated fusion of LDs has been shown to occur in Drosophila S2 cells lacking Cct1 or Cct2, proteins involved in phospholipid synthesis.
This provided a novel cell system to study rapid regulated fusion between homotypic phospholipid monolayers.
Maintaining the architecture of the Golgi ribbon also requires continuous input of membranes from the ER [ 6] and regulated lateral fusion of analogous cisternae [ 7].
Intriguingly, mmp9 and mmp13 were also up-regulated during fusion of vertebral bodies in salmon.
We established a genetically encoded, small-molecule-regulated fusion between a destabilized mutant of FK506 binding protein 12 and constitutively active HSF1 (FigureHSF1A Figure 1A).
Thus, in the case of Sx1A/Munc18a the SNARE complex controls a tightly regulated fusion pathway (regulated exocytosis), and Munc18a binds preferentially to Sx1A in the closed conformation with high affinity [7].
In the mouse, genetically directed neuronal labeling has typically been achieved by the selective expression of a fluorescent protein or enzyme under the direct control of a cell-type-specific promoter or under the indirect control of a pharmacologically-regulated fusion between Cre recombinase and a mutated estrogen receptor ligand-binding domain [CreER; 13] [16].
Fusion of the androgen-regulated gene transmembrane protease, serine 2, TMPRSS2, to the v-ets erythroblastosis virus E26 oncogene homolog (avian), ERG, of the erythroblast transformation-specific (ETS) family is the most common genetic alteration in prostate cancer (PCa).
As a seminal discovery [ 5], many prostate tumors contain a specific genetic change that involves the fusion of an androgen-regulated gene with an oncogene.
Fusion of the androgen-regulated gene, TMPRSS2, with ERG occurs in up to 60% of prostate cancers and is likely to account for the majority of ETS oncogene rearrangements in prostate cancer (Attard et al, 2008).
