Exact(6)
Although necrosis was traditionally considered as an unregulated form of cell death, it is now known to have regulated components, such as those involving receptor-interacting protein (RIP) kinases.
In principle, hyperarcs can connect an arbitrary number of start nodes (regulating components) with an arbitrary number of end notes (regulated components).
The coherence test incorporates the knowledge that a signature is comprised of two oppositely regulated components (i.e. up and down arms) in order to assess the robustness of the signature when it is analyzed in independent datasets.
The pathway was inspected for regions of regulated components and some of the interesting observations are shown in Figure 5.
Basic physiology tells us that SvO2 is not a regulated variable but an adaptive variable depending on four elementary regulated components: VO2 needs, SaO2, Hb and CO.
For instance, at the transcriptomic and the proteomic levels, Gene Ontology (GO) analysis of regulated components indicated that protein synthesis pathways were up-regulated with increasing growth rate [ 8].
Similar(54)
The UPR regulates components of this pathway, which includes membrane trafficking mediators as well as vacuolar proteases [4].
The CP has two primary functions, 1) to produce and regulate components of the cerebral spinal fluid, and 2) to inhibit entry into the brain of exogenous substances.
On the other hand, the gene for Zbtb16 (aFD = 1.6, also known as Plzf) can interact with and regulate components of the renin-angiotensin system.
We speculate that changes in C2GnT1 and C2-O-sLeX expression may alter the expression and function of other adhesion molecules on cancer cells or regulate components of the extracellular matrix known to participate in invasive events.
The active kinase triggers phosphorylation of the retinoblastoma protein (RB), relieving its transcriptional repressive activities and its capacity to regulate components of the DNA replication and G2/M progression [1], [2].
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