Sentence examples for regulated categories from inspiring English sources
The current Gene Set Enrichment Analysis resulted in two significantly regulated categories- protein biosynthesis and carbohydrate metabolism.
The above discussed GSEA results might have masked regulated categories if they contained few differentially regulated genes but a high number of unregulated genes.
The lowest numbers of differentially regulated categories were detected between roots - Fe, nas4x-1 vs. wild type, and leaves + Fe, nas4x-1 vs. wild type.
We conclude from these numbers of regulated categories that + Fe nas4x-1 mutant root cells had approximated the cellular status present in - Fe wild type roots, while + Fe nas4x-1 mutant leaf cells had reacted closest to those of + Fe wild type cells.
On the other other hand, the number of differentially regulated categories was low when comparing nas4x-1 samples with each other (in total eight categories belonging to five areas, Tables 1 and Additional file 3, Table S1) and nas4x-1 wild wild type at - Fe (in total five categories belonging to two areas, Tables 1 and Additional file 3, Table S1).
In leaves, photosystem regulation was apparent as major regulated category.
Note that even thought some of these additional genes are likely directly regulated by FnrL they have remained in the "indirectly regulated" category (Additional file 2: Table S2) as it will require additional experimentation to determine which of genes are indeed under direct control by FnrL.
We demonstrated by DNA microarray analysis that the categories of cell envelope and transport/binding proteins are the most actively regulated gene categories in the ΔrovA mutant, and this was validated by subsequent experiments showing that the cell membranes of the mutant bacteria were both structurally and functionally disrupted.
Other differentially regulated GO categories included pentose metabolism and sterol metabolism being enriched in regulated genes in MWAT and SWAT, but not in EWAT (Table 1).
A threshold of p ≤ 0.05 was chosen to be appropriate to identify significantly regulated GO categories.
Analysis of differentially regulated functional categories confirmed that the nas4x-1 mutant is defective in metal homeostasis.
