Exact(8)
The net effect is that astroglia demarcate gray matter regions, both cortical and subcortical, into functional compartments whose internal activation thresholds and external outputs are regulated by single glial cells.
Other components are typically regulated by single metabolites or groups of biochemically related metabolites.
Previous work infer TFAs from expression levels of genes regulated by single factors or in combination [ 2, 5- 8, 10].
In the top-down analysis, the significance scores of the motifs regulated by single TF or paired-TF are described in Figure 3A.
In some common diseases, the enzymatic isoforms, their assembly, and their possible impairment in the membrane are mainly regulated by single fatty acids.
According to the test, the complexes which were regulated by single miRNAs or miRNAs in the same clusters were ranked higher than the ones which were regulated by multi-miRNAs in different clusters.
Similar(52)
Adhesion of leukocytes to endothelia and their subsequent paracellular movement is regulated by single-span transmembrane JAMs [ 181].
Moreover, looping is not easily reconciled with evidence that some other exons are regulated by single-pyrimidine tracts (Shen et al, 2004; Izquierdo et al, 2005), and an alternative model is that extended complexes propagate along the RNA from the initial high-affinity site(s) (Eperon et al, 2000; Wagner and Garcia-Blanco, 2001; Zhu et al, 2001; Spellman and Smith, 2006).
Alternatively, because it is suggested that the pathogenic mechanism underlying the development of cataract in SAMP strains is different from that of murine hereditary cataract, which is generally regulated by single-gene mutations [ 60], the Gja3 mutation alone may not be sufficient to cause cataract.
This level of detail is omitted here because it does not influence the arguments made in this section; in Sources of noise section, we will, however, treat all of these processes explicitly for the case of a single gene regulated by a single transcription factor.
It also corroborates the finding that, when a single disease is being regulated by a single miRNA, that same miRNA is regulating one another disease thus implying a non-direct way (i.e. via a miRNA) of a disease affecting another disease.
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