Sentence examples for regulated by functional from inspiring English sources

There is evidence that the level of activity of IL-6 and its receptor are regulated by functional polymorphisms in the corresponding genes [ 17].

64b Altogether, these studies indicate that NAD+ signaling in the cell is tightly regulated by functional interplay between NAD+ synthesis and consumption as well as by crosstalk between the enzymes involved in these biological processes.

In this study, we demonstrate that the SHH target GLI3 is regulated by a functional interaction between a MID1-α4-PP2A complex-dependent regulation domain of GLI3 and the MID1-α4-PP2A complex.

The 3 canonical members of the mammalian Ras gene family (H-ras, N-ras, and K-ras) code for four distinct protein isoforms (H-Ras, N-Ras, K-Ras4A and K-Ras4B) which cycle continuously between active (GTP-bound) and inactive (GDP-bound) conformations in a process regulated by their functional interactions with negative (GAP) and positive (GEF) cellular regulators.

It has become increasingly apparent that gene expression is regulated by the functional interplay between spatial genome organization and nuclear architecture.

CYP1B1 activity is regulated by several functional non-synonymous single-nucleotide-polymorphisms (SNPs).

The interaction between NFKB1 promoter nucleotide sequence and C/EBPβ was regulated by the functional SNP rs4648068 in SGC-7901 cells.

Oxidative stress often causes cell death via apoptosis that is regulated by certain functional genes and their protein products.

Our findings support the following model: cell invasion was regulated by the functional interaction between FASN and HER2 in HER2-overexpressing SKBR3 and BT474 breast cancer cells.

From studies in different model organisms it is clear that development of polarity is a gradual process, which can be regulated by a functional hierarchy of protein complexes.

Therefore, we assumed that the decrease in Orai1 expression and ISOC density following the induction of LNCaP cell differentiation by androgen withdrawal occurs because orai1 gene expression might be regulated by the functional AR.