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Apoptosis of mature T lymphocytes is regulated by extensive networks of signal-transduction pathways.
Meanwhile, it is known that the clock genes are regulated by extensive alternative splicing, which is influenced by low temperatures.
Embryonic development is regulated by extensive transcriptional networks that drive cell-specific patterns of gene expression [ 1, 2].
Plant responses to environmental limiting factors are regulated by extensive transcriptional regulatory networks that trigger specific gene expressions [ 63– 63].
However, biosynthetic pathways are often highly intertwined, regulated by extensive feedback mechanisms and require the correct organization of the individual entities in space and time.
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The dpp gene is regulated by an extensive set of enhancers some of which are located approximately 30 kb downstream of the dpp coding region (Fig. 1A; [1A]).
The Hippo signaling pathway can also be regulated by an extensive network of protein filaments found within cells, called the cytoskeleton.
The many loci differentially regulated by MT19c suggest extensive changes in epigenetic control by MT19c.
When the functions of NPM3 are elucidated, it will be of interest to determine the contribution of phosphorylation to these activities, since the functions of both nucleoplasmin and nucleophosmin are regulated by phosphorylation, which is extensive in both proteins [ 7, 17]).
Motor function is regulated by dopaminergic corticostriatal circuitry, and extensive evidence points to disruption of these networks in ADHD (see: del Campo et al., 2011).
Gene ontology of the transcriptome differentially regulated by RGL2, as well as extensive cross-comparison with other available microarray data indicates that RGL2-mediated inhibitiof of germination causes seeds to enter a state of dormancy.
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