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EGFR and other ERBB receptors are known to be regulated by endocytosis.
The functions of ErbB2, ErbB3, and ErbB4 are also regulated by endocytosis to some extent, although the current knowledge of these processes is sparse.
These results suggest the surface expression of KIAA0319 is regulated by endocytosis, supporting the idea that the internalization and recycling of the protein may be involved in fine tuning its role in neuronal migration.
MT1-MMP is able to internalize into the intracellular space, and like other membrane-binding molecules it is regulated by endocytosis because of the functional role of internalization in the cytoplasmic tail [ 43].
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Dear Editor, The presence and abundance of proteins in the plasma membrane (PM) is regulated by exocytosis and endocytosis.
mGluR1 is regulated by constitutive endocytosis, a process that is subject to retardation upon binding of Homer proteins to mGluR1 [41] [43].
The signaling duration and intensity of transmembrane RTKs stimulated by extracellular ligands is regulated by receptor endocytosis, which is characterized as a membrane and vesicular trafficking process.
Surface levels of the membrane-spanning NG2 protein are regulated by clathrin-mediated endocytosis in mouse embryonic fibroblasts15.
Signaling receptors are internalized and regulated by clathrin-mediated endocytosis (CME).
The synaptic abundance of GLR-1 is regulated by ubiquitination and endocytosis [24], [27], [32], [33].
Therefore, we suggest that itga5-dependent SPARC internalization is regulated by clathrin-mediated endocytosis.
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