Sentence examples for regulated by direct from inspiring English sources

Therefore, taken together, these results suggest that BHMT activity can potentially be regulated by direct redox-regulation of critical cysteine residues via Nox4-generated H2O2.

Thus it will be important to determine the fraction of co-regulated genes whose expression is regulated by direct binding of NR3C1 versus other indirect mechanisms of regulation.

The findings represent the first known phenotypic changes triggered by GLTP overexpression and regulated by direct interaction with a p120-catenin protein family member.

Whilst many proteins, such as EGF receptor [15] and protein kinase C [16] are negatively regulated by direct interaction with caveolin-1 through its scaffolding domain, there are some instances where association with caveolin-1 is essential for activation, such as in adipocytes where interaction of the insulin receptor with caveolin-1 is required for successful insulin signaling [17].

In addition, (AnxA2 2- p11 2 association to the plasma membrane seems to be regulated by direct binding of the heterotetramer to phosphatidylinositol (4,5) bisphosphate [34], [35] and p11 itself seems to play a role in the trafficking of some ion channels and receptors — reviewed in [8].

For example, Tiam1 is known to be regulated by direct binding to activated Ras [ 54].

The whisper network is an informal but relatively orderly reporting method, regulated by the direct accountability of a social ecosystem: if I give you false information, then my credibility and relationships will suffer.

Under this system, production, distribution, and exchange are regulated by the direct social obligations of parties involved with one another over an extended period.

Despite having a CNBD, vertebrate EAG family channels are not regulated by the direct binding of cyclic nucleotides [16], [17].

mRNAs regulated by a direct Microprocessor cleavage mechanism should be upregulated in cells deficient for the Microprocessor, but not in Dicer deficient cells.

We also demonstrated that the expression of DKK2 is regulated by the direct interaction of the chimeric protein EWS/ETS with EBS located in the promoter region of the gene.