Sentence examples for regulated by binding from inspiring English sources

Beyond regulation of proteolytic activities by alternative incorporation of catalytic subunits, protein degradation by the proteasome is regulated by binding of proteasomal regulators to the catalytic 20S core particle.

NDR1/2 are also regulated by binding to hMOB2, which is a level of regulation that does not exist with LATS1/2, since hMOB2 does not bind to LATS1/2 [ 39]. hMOB2 competes with hMOB1A/B for binding to the NTR of NDR1/2, where hMOB2 binding appears to be inhibitory, while hMOB1A/B binding is activating [ 59].

In mammalian cells, cell cycle progression is governed by distinct cyclin-dependent kinases (cdks) whose activities are regulated by binding of their activating cyclin subunits and through negative regulation by inhibitor proteins such as p21.

In addition to the regulation of gene transcription, initiation of DNA replication has been proposed to be regulated by binding of replication machinery to the nuclear scaffold/matrix [20], [46].

For nuclear estrogen receptor mediated effects via regulation of gene activity (nuclear estrogen receptors are transcription factors whose activity is regulated by binding to estrogen), prior studies have typically shown a 1,000-fold 1,000-foldvity for BPA relowere to estractivity potent estrogenic drugs, including DES and ethinylestradiol.

This conformational dynamics is physiologically regulated by binding events and post-translational modifications, but can also be affected by pathogenic mutations.

Some Spo0A-regulated genes are regulated by Spo0A binding to sequences (0A boxes) located upstream of the ORF [27], [28].

However, in the preceding paper (DOI: 10.1021/bi500224t), we show that nucleosome binding by ISWI is not regulated by nucleotide binding.

The amount of CYP33 available to bind to MLL PHD3 may be regulated by its binding to RNA.

Much open-source software is regulated by legally binding licenses that give users wide latitude to alter and even commercialize the code.

In the words of the New York Times expert on the subject, Michael Gordon, military competition was regulated by "detailed, binding treaties that spelled out carefully negotiated limits and verification measures".