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We therefore conclude that it is well possible that osteocytes regulate the turnover of mineralized growth plate cartilage.
MMPs and TIMPs regulate the turnover of ECM proteins [ 52].
Mitochondrial PDC acts to regulate the turnover of pyruvate into the fatty acid precursor acetyl-CoA.
Importantly, the phosphorylation status of FE65 Ser was shown to regulate the turnover rate of APP.
Autophagy is an evolutionarily conserved process by which eukaryotic cells regulate the turnover of long-lived proteins and cytoplasmic organelles.
SV40 large T-antigen was found to bind F-box receptor Fbw7 of CRL1 and regulate the turnover of substrate cyclin E [ 132].
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The E3 ligase Pirh2 regulates the turnover and function of proteins involved in cell proliferation and differentiation, cell cycle checkpoint regulation, and cell death (Halaby et al., 2013).
Forest type is a great biotic manipulator in regulating the turnover of soil organic matter via the quantity and quality of litter input or through the modification of soil biophysical properties.
These data suggest an involvement of USP19 in regulating the turnover of p27Kip1.
However JNK2 silencing resulted in a ∼3 fold increase in p53 protein (Fig. 1B) suggesting that JNK2 directly or indirectly regulates the turnover of p53 protein.
It has been shown that JNK regulates the turnover of JunB through its accelerated degradation induced by JNK-mediated phosphorylation of the E3 ligase Itch [23].
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