Sentence examples for regulate the suppression from inspiring English sources

Hence, these results may suggest that Pol κ- immunodepleted extracts are not able to regulate the suppression of origin firing after UV-induced fork stalling and that Pol κ is epistatic to ATR/Chk1.

Such structural modifications in P1-mm may have led to the variable activity of the epigenetic silencing mechanism that in P1-wr stably regulates the suppression in pericarp tissue.

It is also possible that some protein inhibitor of APC is involved in ciliogenesis, regulating the suppression and activation of APC activity during ciliary maintenance and disassembly respectively.

This latter finding seems to be at odds with a previous report that IL-12 directly regulates the suppression of CXCR3 expression of effector CD8+ T cells (Slutter et al., 2013).

The tumor suppressor role of RUNX2 and RUNX3 mainly relates to the antagonism between RUNX2/3 and the cancer-promoting program of ER signaling, whereas the tumor suppressor role of RUNX1 largely correlates to its ability to positively regulate the tumor-suppression program of ER signaling.

Although the frequency of EGFR active mutation in oral carcinomas is controversial (Hsieh et al, 2011; Mclntyre et al, 2012), MALT1 may negatively regulate the pathway by the suppression of gene expression regardless of the presence or absence of mutation.

Because ISG15 interferes with ubiquitylation in tumor cells [33], it prompted us to test the possibility that ATM may regulate the ubiquitin/26S proteasome pathway through suppression of ISG15.

p63 has also been shown to regulate the expression of miR-155, thus promoting tumour suppression and metastasis suppression in epithelial cancer cell lines.

These domains can allosterically regulate the activity of the kinase domain through intramolecular engagement and suppression of the catalytic domain.

Furthermore, we controlled the average size of complex PCR products over a wide range, and simultaneously amplified targets from 0.25 to 10 kb by regulating the degree of suppression in a single-primer PCR.

Despite the acceptance that pregnancy is associated with suppression of cell-mediated immune responses, the mechanisms regulating this suppression are not well defined [ 15].