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These results demonstrate that deleting the Ig1 domain of Robo1 does not disrupt Comm's ability to regulate the receptor in embryonic neurons.
Here, we provide additional evidence of the potential possibility that androgens regulate the receptor of one of the growth factors that stimulate prostate growth, and loss of androgen regulation in PCa may be one of the factors that contribute to the androgen independence of PCa.
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This finding implies that neurons can control the spatial localization of glutamate receptors along neurites by regulating the balance of the different endocytosis pathways that regulate the receptors.
Single particle approaches have further [28, 29] revealed the heterogeneity of two-dimensional trajectories occurring on the neuron surface, suggesting that there are several biophysical processes involved in regulating the receptor motion.
If the concentration dynamics of CheR (the enzyme regulating the receptor methylation) is described as a stochastic process, the model predicts a power-law run length distribution.
In turn estrogens may increase cellular IGF1 through crosstalk, and IGF1 may up-regulate the receptor response to estrogens[ 61].
We found that forced expression of ephrin-A1 down regulated the receptor EphA2 and inhibited cell proliferation and tumor growth in 3D matrigel.
The global activator GacA up–regulates the receptors LasR and RhlR of the first and second QS system, whereas the activator Vfr only up–regulates LasR [ 12, 13].
We now report that different toll-like receptor (TLR) ligands selectively regulate the VPAC2 receptor gene and show a gene repression system controlled by key protein kinase signalling cascades in macrophages.
When Ford joined the lab, Fischbach and his staff were trying to determine whether neuregulin could regulate the muscarinic receptor.
However, the question of how ARA54 and ubiquitin directly regulate the androgen receptor is still unanswered.
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