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The study and use of cell fusion has been an invaluable tool in somatic cell genetics, and it has highlighted the complexity of the mechanisms that regulate the maintenance of the determined and differentiated states.
Taken together, this data strongly suggests KLF family members regulate the maintenance of ES cell pluripotency.
Hes genes are essential effectors of Notch signaling that regulate the maintenance of undifferentiated cells [ 20].
NANOG and OCT4 regulate the maintenance of pluripotent state in embryos and derived cells in most mammalian species [ 43, 44].
OCT4 and NANOG regulate the maintenance of pluripotent state in embryos and derived cells in most mammalian species [ 48, 49].
Notch signaling is known to regulate the maintenance of various types of stem cells (Artavanis-Tsakonas et al. 1999).
Similar(43)
The SLT2/MPK1gene that encodes a serine/threonine MAP kinase involved in regulating the maintenance of cell integrity [ 9, 16- 18] was up regulated approximately 2-fold in the myo1Δ strains (Table 1 and Additional file 1).
And as a legislator, she quickly discovered that New Hampshire had no law regulating the maintenance of records at piercing parlors.
Our study also provides a structural basis for designing inhibitors of USP7 that specifically regulates the maintenance of DNA methylation.
Furthermore, a conceptually new mechanism that regulates the maintenance of axon positioning at the midline has been described in C. elegans.
In mixed forests, the impact of limiting (biotic and abiotic) factors on tree reproductive success regulates the maintenance of species in balanced proportions or the conversion towards monospecific forests.
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