Sentence examples for regulate the innate from inspiring English sources

Previous studies have also shown that mature enterocytes regulate the innate immune inflammatory response by expressing specific negative regulators of innate inflammatory response genes which result in controlled activation to inflammatory stimuli [11] [13].

Among these miRNAs, miR-146a in particular has been reported to negatively regulate the innate immune response by targeting interleukin-1 receptor associated kinase 1 (IRand) and tumor necrosis factor receptor associated factor 6 (TRAF6) in monocyte and moDC.

In addition, mutant PS expressing and PScDKO mice both show abnormal neuroinflammatory responses suggesting that PS may function to regulate the innate immune response in the CNS [9], [13].

The studies of infection with the intracellular bacteria Rhodococcus equi have demonstrated that galectin-3 may regulate the innate immune response by diminishing IL-1β production by macrophages [13].

NPR1 shares homology with IκBα transcription inhibitors, which regulate the innate immunity response [ 21, 24].

One peculiar characteristic of some of these receptors is their ability to regulate the innate and adaptive immune system.

It removes K-63 linked poly-ubiquitin chains from RIP1, TRAF6, RIP2, and NEMO and negatively regulates the innate immune responses (Coornaert et al., 2009).

Our studies use both isolated AECII mouse cells and animals (including knockout mice) and demonstrate that the chemokine MCP-1 can up-regulate the innate immunity of AM.

Furthermore, although they are both immune cells, their functions are highly different, and thus, they have different strategies in regulating the innate and/or adaptative responses against pathogens.

Interestingly, the loss of the transcription factor T-bet, which regulates the innate immune system, influences bacterial populations in the murine gut in a way that they become colitogenic and this colitis is communicable to genetically intact hosts [37].

They found a previously unrecognized anti-inflammatory role of fetuin in counter-regulating the innate immune response, and suggest that it may be possible to use fetuin as an experimental anti-inflammatory agent.