Furthermore, transcallosal fibers have been shown to regulate the efficacy, or gain, of sensory input, for example, during sensory perception.
Together, these results validate our primary screen and suggest that these miRNAs may regulate the efficacy of HR-mediated repair of DSBs.
There is evidence that CB1 receptors are linked to glutamatergic neurotransmission in the mesocortical/ventral striatal circuit that is believed to regulate the efficacy of divers reinforcers including food, opiates and psychostimulants (Bellocchio et al., 2010).
Whereas various mechanisms that regulate the efficacy of synaptic inhibition have been identified (Olmos-Serrano et al., 2010; Cherubini, 2012), our knowledge regarding the modulation of tonic inhibition is far less complete.
A corollary of the above interpretation is that Plk1 activity contributes to regulate the efficacy of Mad2 in SAC signaling, so that less Mad2 is needed for SAC functionality in the absence of Plk1 than in its presence.
However, more recently, it has been shown that a Purkinje cell's response to its climbing fiber input can be graded, which, in turn, can regulate the efficacy of climbing fiber stimulation to induce plasticity in vitro and in decerebrate preparations (Weber et al., 2003; Carey and Regehr, 2009; Maruta et al, 2007; Mathy et al., 2009; Rasmussen et al., 2013).
The results show that DARPP-32 plays a central role in regulating the efficacy of dopaminergic neurotransmission.
An analysis of the literature on feedforward inhibition in CA1 suggests that plasticity at inhibitory synapses might also be able to play a role in regulating the efficacy of CA3-CA1 transmission.
This implies that the KIF5A tail may be important in regulating the efficacy of TRAK2/KIF5A association.
In the simulation, the dopaminergic efflux regulates the efficacy in the initiation, termination and lock-in of basal ganglia selection.
SirT1 therefore positively regulates the efficacy of the estrogen IGF-1 signaling for ductal estrogen IGF-1l proliferation and differentiation.
